Influenza Vaccine in Singapore: A Dual Benefit for Respiratory and Cardiovascular Health

Introduction

Elderly man with mask on sitting down to wait for his turn for doctor consultation.
Elderly woman placing her hands on her chest area after feeling chest pains.
Elderly woman placing her hands on her chest area after feeling chest pains.

The influenza vaccine is commonly recognized for its primary function - to reduce the incidence and severity of seasonal flu. However, there is scientific evidence that suggests a potential secondary benefit; it may reduce the risk of adverse cardiovascular events such as stroke and heart attacks1. This article aims to explain the complex relationship between influenza, coagulation pathways, and cardiovascular health, while highlighting the advantages of influenza vaccination.

Coagulation and its Pathways

The human body has an intricate coagulation system designed to prevent excessive bleeding in case of injury. This system consists of a series of biochemical reactions involving clotting factors, ultimately leading to the formation of a blood clot. Occasionally, these pathways can become dysregulated, resulting in abnormal clot formation within the vascular system, potentially leading to conditions like stroke or myocardial infarction.

Influenza's Impact on Coagulation

Influenza is more than just a respiratory illness; it has a systemic impact, affecting various bodily functions. During a flu infection, the body's immune system releases inflammatory substances that can alter coagulation pathways. This inflammatory response may make the blood more prone to clotting, thereby increasing the risk of cardiovascular events, especially in those with pre-existing cardiovascular conditions.

Cardiovascular Risks and Benefits of Vaccination

Nurse administering influenza vaccine to female patient at clinic.
Elderly couple feeling confident and strengthened after going for influenza vaccination.
Elderly couple feeling confident and strengthened after going for influenza vaccination.

While the primary goal of influenza vaccination remains the prevention of flu and its immediate complications, data from scientific study suggests potential cardiovascular benefits. Some studies have reported a lower incidence of adverse cardiovascular events, such as stroke and heart attack, among individuals who received the influenza vaccine1.

Influenza Vaccination at Central 24-HR Clinic: Prices and Subsidies

Given the potential dual benefits for both respiratory and cardiovascular health, the influenza vaccine represents a cost-effective preventive measure, especially for high-risk populations.

Our vaccination prices for influenza are subsidized for eligible individuals and are as follows2:

Age Group Vaccination Prices
Eligible Singapore children between 6 months to 59 months (<5 years) $0
Eligible Singapore citizens aged 65 years and above Healthier SG patients: $0 (if you undergo vaccination at your enrolled Healthier SG clinic)
Pioneer Generation: $9
Merdeka Generation (from 65th birthday): $18
Eligible Singapore citizens aged 18 to 64, or adolescents aged 5 to 17, with certain medical conditions such as Diabetes, Chronic Kidney Disease, Chronic Liver Disease (Hepatitis B)^ CHAS Blue / CHAS Orange: $18
CHAS Green / Non-CHAS: $35
For all other adults: $70

You may also be eligible to use Medisave to pay for your vaccination. Please talk to our friendly staff for more information.

^Specific medical conditions include:

  • Chronic disorders of the pulmonary or cardiovascular systems, including asthma;
  • Requires medical follow-up or hospitalisation due to chronic metabolic diseases (including diabetes mellitus), renal, neurologic, hepatic, or haematologic disorders;
  • Immunosuppression (including immunosuppression caused by medications, HIV or other immunodeficiencies);
  • Persons aged 18 years (as well as those below 18 years under the NCIS) who are receiving long term aspirin therapy and therefore might be at risk for developing Reye syndrome after influenza infection;
  • Women at all stages of pregnancy; or
  • Persons receiving Intermediate and Long Term Care (ILTC) services.

Source: https://book.health.gov.sg/flu

Conclusion

While the influenza vaccine's primary role is to prevent the onset and severity of the flu, there is scientific evidence that suggests that it may also offer cardiovascular benefits. These potential benefits make the vaccine an even more valuable tool in public health, especially for those at high risk of cardiovascular events. If you have a condition or concern, talk to our friendly staff through WhatsApp at 88771706.

References

1. Association of Influenza Vaccination With Cardiovascular Risk:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9055450
2. VACCINATION AND CHILDHOOD DEVELOPMENTAL SCREENING SUBSIDIES:
https://www.moh.gov.sg/healthcare-schemes-subsidies/vaccination-and-childhood-developmental-screening-subsidies